Quick answer
There is no official daily amount for lemon balm. Single-dose studies used 300 to 1,600 mg, and sleep trials used 400 mg a day of one extract, or 600 mg a day of another, for two to three weeks. The longest trial gave an extract with 500 mg of rosmarinic acid daily for 96 weeks.1,2,3,4,5,6
Key facts
- In one study, 1,600 mg of dried leaf raised calm and memory scores, while lower doses slowed memory tasks.2
- The 400 mg a day used in both placebo-controlled sleep trials came from one phospholipid-bound extract.3,4
- A single dose of extract with 500 mg of rosmarinic acid caused no changes in liver, kidney or blood tests.7
- No upper limit has been set for lemon balm.2,6
The amounts used in studies
| Study | Product | Amount | How long |
|---|---|---|---|
| Mood, 20 young adults | Standardized extract | 300, 600 or 900 mg once | Single doses a week apart |
| Mood and memory, 20 young adults | Dried leaf | 600, 1,000 or 1,600 mg once | Single doses a week apart |
| Stressful task, 18 adults | Standardized extract | 300 or 600 mg once | Single doses a week apart |
| Demanding tasks, 106 young adults | Extract | 300 mg once | One test day |
| Sleep, 100 adults | Phospholipid-bound extract | 200 mg twice a day | 3 weeks |
| Sleep, 30 adults | Phospholipid-bound extract | 400 mg each evening | 2 weeks |
| Sleep and tension, 20 adults, no placebo | Leaf extract | 300 mg twice a day | 15 days |
| Memory, 323 older adults | Extract rich in rosmarinic acid | 500 mg of rosmarinic acid a day | 96 weeks |
Amounts do not transfer from one product to another. In the single-dose studies, calm rose at 300 mg of one extract but needed 1,600 mg of dried leaf, and 900 mg of the extract lowered alertness instead.1,2
An open trial without a placebo group used 600 mg a day, as 300 mg in the morning and 300 mg in the evening before sleep, for 15 days.5
In a Japanese trial, older adults took an extract providing 500 mg of rosmarinic acid a day for 96 weeks.6
Lemon balm dosage for sleep
The two placebo-controlled sleep trials used 400 mg a day of a phospholipid-bound extract, either as 200 mg twice a day or as 400 mg in the evening.3,4
May improve self-rated sleep quality, in short trials of one extract*3,4,5
Early evidence
Two randomized trials tested the same phospholipid-bound extract at 400 mg a day. In 100 adults with poor sleep or moderate stress, three weeks lowered scores on a standard sleep quality questionnaire much more than placebo, but the lemon balm group started with worse sleep. In a crossover trial of 30 adults, 400 mg taken 30 minutes before bed for two weeks lowered a sleep difficulty score by 2.9 points more than placebo; its lead author directs the company that sells the product. An earlier 15-day open trial of 600 mg a day of another extract had no placebo group.
Amount studied: 400 mg a day of a phospholipid-bound extract for two to three weeks
Both placebo-controlled trials used the same branded extract at 400 mg a day. Neither tested a smaller amount or a different extract, so there is no evidence on whether those would give the same result.3,4
Lemon balm tea
We found no trial of lemon balm tea on its own, so there is no studied number of cups a day. FDA lists lemon balm as generally recognized as safe as a food flavoring, which covers its use in foods and drinks rather than supplement doses.10
What's in ours
What’s in ours
- Sleep: Lemon Balm Extract, 100 mg per serving, from the label
A two-capsule serving of our Sleep formula has 100 mg of lemon balm extract. That is a quarter of the daily amount in the sleep trials and below the smallest single dose in the mood studies.1,3
Children
We found no trial that set a dose of lemon balm alone for children. Infants have been given lemon balm only in mixtures with other herbs, which says nothing about a dose of lemon balm by itself. Ask a pediatrician before giving it to a child.10
How much is safe
No upper limit has been set for lemon balm. Studies have used single doses of up to 1,600 mg, and an extract providing 500 mg of rosmarinic acid a day for 96 weeks.2,6
A single dose of extract with 500 mg of rosmarinic acid did not change liver, kidney or blood count tests in 11 healthy adults.7
In single-dose studies, the highest dose of one extract lowered alertness for several hours, and some doses slowed timed memory tasks.1,2
If you try a larger single dose, expect that you may feel less alert, and do not drive until you know how it affects you.1
Questions people ask
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Sources
- Kennedy DO, Scholey AB, Tildesley NT, Perry EK, Wesnes KA. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav. 2002;72(4):953-964. Opened 2026-10-07.
- Kennedy DO, Wake G, Savelev S, et al. Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology. 2003;28(10):1871-1881. Opened 2026-10-07.
- Bano A, Hepsomali P, Rabbani F, et al. The possible calming effect of subchronic supplementation of a standardised phospholipid carrier-based Melissa officinalis L. extract in healthy adults with emotional distress and poor sleep conditions: results from a prospective, randomised, double-blinded, placebo-controlled clinical trial. Front Pharmacol. 2023;14:1250560. Opened 2026-10-07.
- Di Pierro F, Sisti D, Rocchi M, et al. Effects of Melissa officinalis Phytosome on Sleep Quality: Results of a Prospective, Double-Blind, Placebo-Controlled, and Cross-Over Study. Nutrients. 2024;16(23):4199. Opened 2026-10-07.
- Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011;4(3):211-218. Opened 2026-10-07.
- Noguchi-Shinohara M, Hamaguchi T, Sakai K, et al. Effects of Melissa officinalis Extract Containing Rosmarinic Acid on Cognition in Older Adults Without Dementia: A Randomized Controlled Trial. J Alzheimers Dis. 2023;91(2):805-814. Opened 2026-10-07.
- Noguchi-Shinohara M, Ono K, Hamaguchi T, et al. Pharmacokinetics, Safety and Tolerability of Melissa officinalis Extract which Contained Rosmarinic Acid in Healthy Individuals: A Randomized Controlled Trial. PLoS One. 2015;10(5):e0126422. Opened 2026-10-07.
- Kennedy DO, Little W, Scholey AB. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (lemon balm). Psychosom Med. 2004;66(4):607-613. Opened 2026-10-07.
- Mathews I, Eastwood J, Bell L, et al. The acute effects of Zensera (Melissa officinalis L.) extract on mood and cognitive performance during cognitive overload: a randomised placebo-controlled, double-blind study in healthy young adults with moderate subjective stress. Ther Adv Psychopharmacol. 2026;16:20451253261415706. Opened 2026-10-07.
- Lemon Balm. In: Drugs and Lactation Database (LactMed). Bethesda (MD): National Institute of Child Health and Human Development; 2006 onward. Updated March 15, 2026. Read through PubMed. Opened 2026-10-07.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
This page is information, not medical advice. Talk to your doctor or pharmacist about your own situation.