Gut and Immune
Probiotic 40
Forty billion CFU from four strains named on the label.
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Gut and Immune
Bovine Colostrum PowderUnflavored powder · 30 servings
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One container is 30 servings: about 30 days at the label amount.
Contains milk. WADA does not recommend colostrum for athletes who are drug tested.
Contains: Milk.
The whole label
| Serving size 1 scoop (2.3 g) | ||
| Servings per container 30 | ||
| Amount per serving | Amount | % Daily Value** |
|---|---|---|
| Calories | 10 kcal | |
| Calcium | 20 mg | 2%** |
| Sodium | 5 mg | <1%** |
| Potassium | 25 mg | <1%** |
| Bovine Colostrum (25% Immunoglobulin G) | 2,300 mg | *** |
| Immunoglobulin (IgG) | 575 mg | *** |
| **Percent Daily Value is based on a 2,000 calorie diet.***Daily Value (DV) not established. | ||
About the ingredients: Colostrum
Directions
Mix one scoop in 6 to 8 oz of cold water or any cold drink and drink within 10 minutes.
As a dietary supplement, adults use one (1) scoop of powder in 6-8 oz (177-237ml) of cold water or favorite beverage. Consume within 10 minutes of mixing
Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. KEEP OUT OF THE REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.
Graded honestly
Bovine colostrum is the first milk a cow makes after calving, dried to a powder. One scoop gives 2.3 g, with 575 mg of the antibody immunoglobulin G (IgG). Most human research used 10 to 20 g a day. At doses close to this product's, two small trials in athletes found a tighter gut barrier, while a larger trial in healthy adults found no change in immune measures.
Colostrum contains antibodies (mostly IgG), lactoferrin and growth factors, along with ordinary milk proteins and some lactose. Cow antibodies are unlikely to be absorbed intact into the human bloodstream, so any effect is thought to happen inside the gut. Hard exercise makes the gut lining more permeable for a while, and in trials colostrum has blunted that rise. How well a given powder works may depend on how soon after calving it was collected and how it was processed, because the active proteins fall quickly over the first few days and are sensitive to heat.
This product provides 2.3 g a day, with 575 mg of IgG. Most human trials used 10 to 20 g a day.
Gut barrier during exercise: the best-known trials gave 20 g a day for 2 weeks and saw a smaller rise in gut permeability after hard exercise. Two small trials used 1 g a day (500 mg twice daily) for 20 days in athletes and also saw lower permeability. These are the basis for the one benefit above.
In the second of them, colostrum collected 72 hours after calving had no effect, while colostrum collected at 2 or 24 hours did. Some trials at high doses found no effect. Immune measures: in 138 healthy adults aged 40 to 80, 1.2 g a day of a colostrum concentrate (about 500 mg of immunoglobulins, close to this product) for 10 weeks changed none of the immune measures tested.
No immune claim is made. Upper respiratory symptoms, as context only: a meta-analysis of 5 trials in 152 exercising adults found fewer days with symptoms at 10 or 20 g a day for 8 to 12 weeks. It judged four of the five trials at moderate or high risk of bias.
One trial at 0.5 to 1 g a day in 158 university students found no significant difference overall, with a difference only in the medical-student subgroup. These are illness outcomes and are not claims for this product. Strength, body composition and recovery: a 2021 review describes the evidence as limited.
No claim is made.
Helps maintain normal gut barrier function in athletes during hard training
Two small placebo-controlled trials from one research group, in 16 and 31 athletes, found that 1 g a day of freeze-dried colostrum for 20 days lowered a urine-test measure of gut permeability. A 2024 meta-analysis of 10 trials also found lower permeability markers, with very inconsistent results between trials, and most colostrum trials used 10 to 20 g a day. The 1 g trials used colostrum collected within 24 hours of calving. This label does not state collection time or processing, so the match is uncertain. [1][2][3][4]
Strong evidence: many human trials agree, at the amount in this product. Moderate evidence: human trials mostly agree, but they are small, short or mixed. Early evidence: a few small human studies or lab work. Promising, not proven.
Safety
No tolerable upper intake level has been set. Trials have used 10 to 20 g a day for 8 to 12 weeks, and reviewers describe colostrum as generally well tolerated while noting that side effects were poorly reported (Jones 2016). This product provides 2.3 g a day, and the label says not to exceed the recommended dose.
Colostrum is a dairy product. It can be mixed with Collagen Peptides or Plant Protein, but the shake is then no longer dairy-free. It adds only 20 mg of calcium, so there is no mineral overlap of concern.
There is no evidence that taking it with Probiotic 40, Daily Probiotic or L-Glutamine adds benefit.
Lab reports
We hold the manufacturer’s lab report for a production lot of this product. It reports on the manufacturer’s own lot, not on the container you receive. This is what it covers and what it leaves out.
No IgG or protein result is reported.
Answers
It is far less than most studies used, which was 10 to 20 g a day. Two small trials in athletes found an effect on a gut barrier test at 1 g a day, which is why that single benefit is graded as early evidence. Outside that setting, there is no good evidence for this dose.
We do not claim that. In 138 healthy adults, 1.2 g a day for 10 weeks changed none of the immune measures tested. Studies reporting fewer respiratory symptoms in athletes used 10 to 20 g a day, and a supplement may not claim to prevent illness.
Not if you are allergic to milk. It contains milk proteins, including ones that commonly trigger cow's milk allergy. Colostrum also contains lactose. One scoop is small, but the label does not state the lactose content, so start cautiously if you are sensitive.
Follow the label: mix it into cold water or another cold drink and drink it within 10 minutes. The proteins thought to matter in colostrum are sensitive to heat, which is why the colostrum used in the low-dose trials was freeze-dried at low temperature.
It is not banned. WADA's Prohibited List Q&A says colostrum is not specifically prohibited, but that it may contain growth factors that are prohibited and could affect a test, so WADA does not recommend it. A 2021 review concluded that the balance of studies does not show colostrum raising blood IGF-1. If you are tested, check with your federation first.
Probably not. Reviewers consider it unlikely that cow antibodies are absorbed intact by human adults. Any effect is thought to happen inside the gut.
Colostrum is the first milk after calving. It has more protein and more antibodies than regular milk, and those levels fall quickly over the first two to three days. In the low-dose trials, whey was the placebo.
You may not notice anything. The low-dose trials ran for 20 days and measured a laboratory marker in urine, not how people felt. No study at this dose has shown a change in symptoms.
Read the studies
Reviewed 2026-10-01. This page is information, not medical advice.
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.